3G1F

Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5,6-dihydroorotidine 5'-monophosphate

3G1F の概要

• エントリーDOI: 10.2210/pdb3g1f/pdb
• 関連するPDBエントリー: 3G18 3G1A 3G1D 3G1H 3G1S 3G1V 3G1X 3G1Y 3G22 3G24
• 分子名称: Orotidine 5'-phosphate decarboxylase, 5,6-dihydroorotidine 5'-monophosphate (3 entities in total)
• 機能のキーワード: orotidine 5'-monophosphate decarboxylase, h2-omp, decarboxylase, pyrimidine biosynthesis, lyase
• 由来する生物種: Methanothermobacter thermautotrophicus str. Delta H
• タンパク質・核酸の鎖数: 13
• 化学式量合計: 328313.75

構造登録者

Fedorov, A.A.,Fedorov, E.V.,Chan, K.K.,Gerlt, J.A.,Almo, S.C. (登録日: 2009-01-29, 公開日: 2009-06-23, 最終更新日: 2023-09-06)

• 主引用文献: Chan, K.K.,Wood, B.M.,Fedorov, A.A.,Fedorov, E.V.,Imker, H.J.,Amyes, T.L.,Richard, J.P.,Almo, S.C.,Gerlt, J.A.; Mechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: evidence for substrate destabilization.; Biochemistry, 48:5518-5531, 2009; PubMed: 19435314; DOI: 10.1021/bi900623r

実験手法

X-RAY DIFFRACTION (2.5 Å)