3G0Q

Crystal Structure of MutY bound to its inhibitor DNA

Summary for 3G0Q

• Entry DOI: 10.2210/pdb3g0q/pdb
• Descriptor: A/G-specific adenine glycosylase, 5'-D(*AP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*CP*AP*GP*TP*CP*TP*T)-3', ... (6 entities in total)
• Functional Keywords: helix-hairpin-helix motif, dna glycosylase, 8-oxoguanine, protein-dna complex, adenine glycosylase, dna repair, glycosidase, hydrolase, hydrolase-dna complex, hydrolase/dna
• Biological source: Bacillus Stearothermophilus
• Total number of polymer chains: 3
• Total formula weight: 47316.87

Authors

Lee, S.,Verdine, G.L. (deposition date: 2009-01-28, release date: 2009-11-17, Last modification date: 2023-09-06)

• Primary citation: Lee, S.,Verdine, G.L.; Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase.; Proc.Natl.Acad.Sci.Usa, 106:18497-18502, 2009; PubMed: 19841264; DOI: 10.1073/pnas.0902908106

Experimental method

X-RAY DIFFRACTION (2.2 Å)