3FZN

Intermediate analogue in benzoylformate decarboxylase

3FZN の概要

• エントリーDOI: 10.2210/pdb3fzn/pdb
• 分子名称: Benzoylformate decarboxylase, 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, MAGNESIUM ION, ... (7 entities in total)
• 機能のキーワード: benzoylformate decarboxylase, thiamin diphosphate, intermediate analogue, aromatic hydrocarbons catabolism, calcium, decarboxylase, lyase, magnesium, mandelate pathway, metal-binding, thiamine pyrophosphate
• 由来する生物種: Pseudomonas putida
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 232518.81

構造登録者

Bruning, M.,Berheide, M.,Meyer, D.,Golbik, R.,Bartunik, H.,Liese, A.,Tittmann, K. (登録日: 2009-01-26, 公開日: 2009-05-05, 最終更新日: 2023-11-01)

• 主引用文献: Bruning, M.,Berheide, M.,Meyer, D.,Golbik, R.,Bartunik, H.,Liese, A.,Tittmann, K.; Structural and kinetic studies on native intermediates and an intermediate analogue in benzoylformate decarboxylase reveal a least motion mechanism with an unprecedented short-lived predecarboxylation intermediate.; Biochemistry, 48:3258-3268, 2009; PubMed: 19182954; DOI: 10.1021/bi801957d

実験手法

X-RAY DIFFRACTION (1.62 Å)