3FWN

Dimeric 6-phosphogluconate dehydrogenase complexed with 6-phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate

3FWN の概要

• エントリーDOI: 10.2210/pdb3fwn/pdb
• 関連するPDBエントリー: 2ZYA 2ZYG 3FWD
• 分子名称: 6-phosphogluconate dehydrogenase, decarboxylating, 6-PHOSPHOGLUCONIC ACID, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: nadp, pentose phosphate pathway, oxidoreductase, 6-phosphogluconate dehydrogenase, 6-phosphogluconate, gluconate utilization, pentose shunt
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 107263.07

構造登録者

Chen, Y.-Y.,Ko, T.-P.,Lo, L.-P.,Lin, C.-H.,Wang, A.H.-J. (登録日: 2009-01-19, 公開日: 2009-09-01, 最終更新日: 2023-11-01)

• 主引用文献: Chen, Y.-Y.,Ko, T.-P.,Chen, W.-H.,Lo, L.-P.,Lin, C.-H.,Wang, A.H.-J.; Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism; J.Struct.Biol., 169:25-35, 2010; PubMed: 19686854; DOI: 10.1016/j.jsb.2009.08.006

実験手法

X-RAY DIFFRACTION (1.5 Å)