3FUO

The Crystal structure of receptor binding domain of botulinum neurotoxin serotype A

3FUO の概要

• エントリーDOI: 10.2210/pdb3fuo/pdb
• 分子名称: Botulinum neurotoxin type A (2 entities in total)
• 機能のキーワード: botulinum neurotoxin, ganglioside binding, hydrolase, membrane, metal-binding, metalloprotease, neurotoxin, pharmaceutical, protease, secreted, toxin, transmembrane, zinc
• 由来する生物種: Clostridium botulinum
• 細胞内の位置: Botulinum neurotoxin A light chain: Secreted. Botulinum neurotoxin A heavy chain: Secreted: P10845
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 49751.33

構造登録者

Fu, Z.,Chen, C.,Barbieri, J.T.,Kim, J.-J.P.,Baldwin, M.R. (登録日: 2009-01-14, 公開日: 2009-06-16, 最終更新日: 2023-09-06)

• 主引用文献: Fu, Z.,Chen, C.,Barbieri, J.T.,Kim, J.J.,Baldwin, M.R.; Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F; Biochemistry, 48:5631-5641, 2009; PubMed: 19476346; DOI: 10.1021/bi9002138

実験手法

X-RAY DIFFRACTION (1.8 Å)