3FT9

X-ray Crystal structure of pollen allergen - Phl p 3

3FT9 の概要

• エントリーDOI: 10.2210/pdb3ft9/pdb
• 分子名称: Phl p 3 allergen (2 entities in total)
• 機能のキーワード: beta-barrel, allergen
• 由来する生物種: Phleum pratense (timothy)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11378.95

構造登録者

Keller, W.,Devanaboyina, S.C. (登録日: 2009-01-12, 公開日: 2010-01-26, 最終更新日: 2024-05-22)

主引用文献

Devanaboyina, S.C.,Cornelius, C.,Lupinek, C.,Fauland, K.,Dall'Antonia, F.,Nandy, A.,Hagen, S.,Flicker, S.,Valenta, R.,Keller, W.
High-resolution crystal structure and IgE recognition of the major grass pollen allergen Phl p 3.
Allergy, 69:1617-1628, 2014

PubMed Abstract: Group 2 and 3 grass pollen allergens are major allergens with high allergenic activity and exhibit structural similarity with the C-terminal portion of major group 1 allergens. In this study, we aimed to determine the crystal structure of timothy grass pollen allergen, Phl p 3, and to study its IgE recognition and cross-reactivity with group 2 and group 1 allergens.

PubMed: 25123586
DOI: 10.1111/all.12511

実験手法

X-RAY DIFFRACTION (2.05 Å)