3FT2
Crystal Structure of a citrulline peptide variant of the minor histocompatibility peptide HA-1 in complex with HLA-A2
Summary for 3FT2
Entry DOI | 10.2210/pdb3ft2/pdb |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, citrulline variant HA-1 peptide, ... (4 entities in total) |
Functional Keywords | hla, human minor h antigens, antigen processing, antigen presentation, immune response, immunogenicity, membrane, mhc i, polymorphism, transmembrane, immunoglobulin domain, graft rejection, host-versus-graft disease, graft-versus-tumor immune system, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 |
Total number of polymer chains | 3 |
Total formula weight | 44805.77 |
Authors | Reiser, J.-B.,Gras, S.,Chouquet, A.,Le Gorrec, M.,Spierings, E.,Goulmy, E.,Housset, D. (deposition date: 2009-01-12, release date: 2009-04-28, Last modification date: 2023-11-15) |
Primary citation | Spierings, E.,Gras, S.,Reiser, J.B.,Mommaas, B.,Almekinders, M.,Kester, M.G.,Chouquet, A.,Le Gorrec, M.,Drijfhout, J.W.,Ossendorp, F.,Housset, D.,Goulmy, E. Steric hindrance and fast dissociation explain the lack of immunogenicity of the minor histocompatibility HA-1Arg Null allele. J.Immunol., 182:4809-4816, 2009 Cited by PubMed: 19342659DOI: 10.4049/jimmunol.0803911 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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