3FR1
NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)
Summary for 3FR1
| Entry DOI | 10.2210/pdb3fr1/pdb |
| Related | 3FQP 3FTH 3FTK 3FTL |
| Descriptor | Islet amyloid polypeptide, CHLORIDE ION (3 entities in total) |
| Functional Keywords | amyloid-like protofibril, amidation, amyloid, cleavage on pair of basic residues, hormone, polymorphism, secreted, protein fibril |
| Biological source | Homo sapiens (Human) |
| Cellular location | Secreted : P10997 |
| Total number of polymer chains | 1 |
| Total formula weight | 752.26 |
| Authors | Wiltzius, J.J.W.,Sawaya, M.R.,Eisenberg, D. (deposition date: 2009-01-08, release date: 2009-06-30, Last modification date: 2024-02-21) |
| Primary citation | Wiltzius, J.J.,Landau, M.,Nelson, R.,Sawaya, M.R.,Apostol, M.I.,Goldschmidt, L.,Soriaga, A.B.,Cascio, D.,Rajashankar, K.,Eisenberg, D. Molecular mechanisms for protein-encoded inheritance Nat.Struct.Mol.Biol., 16:973-978, 2009 Cited by PubMed: 19684598DOI: 10.1038/nsmb.1643 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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