3FP8

Anionic trypsin variant S195A in complex with bovine pancreatic trypsin inhibitor (BPTI) determined to the 1.46 A resolution limit

3FP8 の概要

• エントリーDOI: 10.2210/pdb3fp8/pdb
• 関連するPDBエントリー: 3FP6 3FP7 3TGI
• 分子名称: Anionic trypsin-2, Pancreatic trypsin inhibitor, 1,2-ETHANEDIOL, ... (7 entities in total)
• 機能のキーワード: enzyme-inhibitor complex, peptide bond hydrolysis, serine protease, calcium, digestion, hydrolase, metal-binding, protease, secreted, zymogen, pharmaceutical, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats); 詳細
• 細胞内の位置: Secreted, extracellular space: P00763; Secreted: P00974
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 31317.37

構造登録者

Zakharova, E.,Horvath, M.P.,Goldenberg, D.P.,Curtice, K. (登録日: 2009-01-04, 公開日: 2009-02-17, 最終更新日: 2023-09-06)

• 主引用文献: Zakharova, E.,Horvath, M.P.,Goldenberg, D.P.; Structure of a serine protease poised to resynthesize a peptide bond.; Proc.Natl.Acad.Sci.USA, 106:11034-11039, 2009; PubMed: 19549826; DOI: 10.1073/pnas.0902463106

実験手法

X-RAY DIFFRACTION (1.46 Å)