3FM8

Crystal structure of full length centaurin alpha-1 bound with the FHA domain of KIF13B (CAPRI target)

Summary for 3FM8

DescriptorKinesin-like protein KIF13B, Centaurin-alpha-1, UNKNOWN ATOM OR ION, ... (6 entities in total)
Functional Keywordskinesin, gap, gtpase activation, structural genomics consortium, sgc, atp-binding, cytoskeleton, microtubule, motor protein, nucleotide-binding, phosphoprotein, metal-binding, nucleus, zinc-finger, metal binding protein, transport protein-hydrolase activator complex, transport protein/hydrolase activator
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytoskeleton  Q9NQT8
Nucleus O75689
Total number of polymer chains4
Total molecular weight119749.97
Authors
Shen, L.,Tong, Y.,Tempel, W.,MacKenzie, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2008-12-19, release date: 2009-08-25, Last modification date: 2017-11-01)
Primary citation
Tong, Y.,Tempel, W.,Wang, H.,Yamada, K.,Shen, L.,Senisterra, G.A.,MacKenzie, F.,Chishti, A.H.,Park, H.W.
Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1.
Proc.Natl.Acad.Sci.USA, 107:20346-20351, 2010
PubMed: 21057110 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1009008107
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.27140.2%0.8%7.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3fm8
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Molmil generated image of 3fm8
rotated about x axis by 90°
Molmil generated image of 3fm8
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 3fm8
no rotation
Molmil generated image of 3fm8
rotated about x axis by 90°
Molmil generated image of 3fm8
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3fm8.pdb2.gz [75.3 KB])
Coordinate files for Biological unit (3fm8.pdb1.gz [78.24 KB])