3FL5

Protein kinase CK2 in complex with the inhibitor Quinalizarin

3FL5 の概要

• エントリーDOI: 10.2210/pdb3fl5/pdb
• 関連するPDBエントリー: 1F0Q 3BQC
• 分子名称: Casein kinase II subunit alpha, DI(HYDROXYETHYL)ETHER, 1,2,5,8-tetrahydroxyanthracene-9,10-dione, ... (4 entities in total)
• 機能のキーワード: protein kinase ck2-inhibitor complex, atp-binding, kinase, nucleotide-binding, serine/threonine-protein kinase, transferase
• 由来する生物種: Zea mays
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39685.49

構造登録者

Mazzorana, M.,Franchin, C.,Battistutta, R. (登録日: 2008-12-18, 公開日: 2009-08-18, 最終更新日: 2017-11-01)

• 主引用文献: Cozza, G.,Mazzorana, M.,Papinutto, E.,Bain, J.,Elliott, M.,di Maira, G.,Gianoncelli, A.,Pagano, M.A.,Sarno, S.,Ruzzene, M.,Battistutta, R.,Meggio, F.,Moro, S.,Zagotto, G.,Pinna, L.A.; Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2; Biochem.J., 421:387-395, 2009; PubMed: 19432557; DOI: 10.1042/BJ20090069

実験手法

X-RAY DIFFRACTION (2.3 Å)