3FJQ

Crystal structure of cAMP-dependent protein kinase catalytic subunit alpha in complex with peptide inhibitor PKI alpha (6-25)

3FJQ の概要

• エントリーDOI: 10.2210/pdb3fjq/pdb
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, MANGANESE (II) ION, ... (5 entities in total)
• 機能のキーワード: nucleotide binding, protein kinase activity, protein serine/threonine kinase activity, camp-dependent protein kinase activity, protein binding, atp binding, kinase activity, transferase activity, alternative splicing, atp-binding, camp, cytoplasm, kinase, lipoprotein, myristate, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase, protein kinase inhibitor
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm . Isoform 2: Cell projection, cilium, flagellum : P05132
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43500.78

構造登録者

Kim, C. (登録日: 2008-12-15, 公開日: 2009-08-04, 最終更新日: 2017-11-01)

• 主引用文献: Thompson, E.E.,Kornev, A.P.,Kannan, N.,Kim, C.,Ten Eyck, L.F.,Taylor, S.S.; Comparative surface geometry of the protein kinase family.; Protein Sci., 18:2016-2026, 2009; PubMed: 19610074; DOI: 10.1002/pro.209

実験手法

X-RAY DIFFRACTION (1.6 Å)