3FIV

CRYSTAL STRUCTURE OF FELINE IMMUNODEFICIENCY VIRUS PROTEASE COMPLEXED WITH A SUBSTRATE

Summary for 3FIV

Entry DOI	10.2210/pdb3fiv/pdb
Related	2FIV
Related PRD ID	PRD_000243
Descriptor	FELINE IMMUNODEFICIENCY VIRUS PROTEASE, ACE-ALN-VAL-LEU-ALA-GLU-ALN-NH2, SULFATE ION, ... (4 entities in total)
Functional Keywords	aspartic protease, retroviral protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Feline immunodeficiency virus
Total number of polymer chains	4
Total formula weight	28450.73
Authors	Schalk-Hihi, C.,Lubkowski, J.,Zdanov, A.,Wlodawer, A.,Gustchina, A. (deposition date: 1997-07-09, release date: 1997-11-12, Last modification date: 2023-08-09)
Primary citation	Laco, G.S.,Schalk-Hihi, C.,Lubkowski, J.,Morris, G.,Zdanov, A.,Olson, A.,Elder, J.H.,Wlodawer, A.,Gustchina, A. Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor. Biochemistry, 36:10696-10708, 1997 Cited by PubMed: 9271500 DOI: 10.1021/bi9707436 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation