3FGW

One chain form of the 66.3 kDa protein

3FGW の概要

• エントリーDOI: 10.2210/pdb3fgw/pdb
• 関連するPDBエントリー: 3FBX 3FGR 3FGT
• 分子名称: Putative phospholipase B-like 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: alpha beta, glycosylated, disulphide bonds, n-terminal hydrolase fold, occupied pocket, one chain form, glycoprotein, hydrolase, lipid degradation, lysosome
• 由来する生物種: Mus musculus (mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 65623.05

構造登録者

Lakomek, K.,Dickmanns, A.,Ficner, R. (登録日: 2008-12-08, 公開日: 2009-09-15, 最終更新日: 2024-11-20)

主引用文献

Lakomek, K.,Dickmanns, A.,Kettwig, M.,Urlaub, H.,Ficner, R.,Luebke, T.
Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography
Bmc Struct.Biol., 9:56-56, 2009

PubMed Abstract: The lysosomal 66.3 kDa protein from mouse is a soluble, mannose 6-phosphate containing protein of so far unknown function. It is synthesized as a glycosylated 75 kDa precursor that undergoes limited proteolysis leading to a 28 kDa N- and a 40 kDa C-terminal fragment.

PubMed: 19706171
DOI: 10.1186/1472-6807-9-56

実験手法

X-RAY DIFFRACTION (2.8 Å)