3FF6

Human ACC2 CT domain with CP-640186

3FF6 の概要

• エントリーDOI: 10.2210/pdb3ff6/pdb
• 関連するPDBエントリー: 1od2 1w2x
• 分子名称: Acetyl-CoA carboxylase 2, (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE (3 entities in total)
• 機能のキーワード: acetyl coa carboxylase, acc2, acc, metabolic disorder, fatty acid metabolism, atp-binding, biotin, fatty acid biosynthesis, ligase, lipid synthesis, manganese, membrane, metal-binding, multifunctional enzyme, nucleotide-binding, phosphoprotein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion : O00763
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 346508.25

構造登録者

Williams, S.P.,Madauss, K.P.,Burkhart, W.A. (登録日: 2008-12-02, 公開日: 2009-05-19, 最終更新日: 2024-04-03)

• 主引用文献: Madauss, K.P.,Burkhart, W.A.,Consler, T.G.,Cowan, D.J.,Gottschalk, W.K.,Miller, A.B.,Short, S.A.,Tran, T.B.,Williams, S.P.; The human ACC2 CT-domain C-terminus is required for full functionality and has a novel twist.; Acta Crystallogr.,Sect.D, 65:449-461, 2009; PubMed: 19390150; DOI: 10.1107/S0907444909008014

実験手法

X-RAY DIFFRACTION (3.19 Å)