3FE4

Crystal Structure of Human Carbonic Anhydrase vi

Summary for 3FE4

Entry DOI	10.2210/pdb3fe4/pdb
Descriptor	Carbonic anhydrase 6, MAGNESIUM ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	carbonic anhydrase, secretion, metal binding, structural genomics, structural genomics consortium, sgc, glycoprotein, lyase, metal-binding, secreted
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P23280
Total number of polymer chains	2
Total formula weight	64133.81
Authors	Pilka, E.S.,Kochan, G.,Krysztofinska, E.,Muniz, J.,Yue, W.W.,Roos, A.K.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2008-11-27, release date: 2008-12-16, Last modification date: 2023-11-01)
Primary citation	Pilka, E.S.,Kochan, G.,Oppermann, U.,Yue, W.W. Crystal structure of the secretory isozyme of mammalian carbonic anhydrases CA VI: implications for biological assembly and inhibitor development Biochem.Biophys.Res.Commun., 419:485-489, 2012 Cited by PubMed: 22366092 DOI: 10.1016/j.bbrc.2012.02.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation