3FBA
Crystal structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with ligand
3FBA の概要
エントリーDOI | 10.2210/pdb3fba/pdb |
分子名称 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, [(2S,3S,4R,5S)-5-(4-amino-2-oxo-pyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate, ... (6 entities in total) |
機能のキーワード | mecdp-synthase, lyase, isoprene biosynthesis, magnesium, manganese, metal-binding |
由来する生物種 | Escherichia coli |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 18371.18 |
構造登録者 | |
主引用文献 | Ramsden, N.L.,Buetow, L.,Dawson, A.,Kemp, L.A.,Ulaganathan, V.,Brenk, R.,Klebe, G.,Hunter, W.N. A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy J.Med.Chem., 52:2531-2542, 2009 Cited by PubMed: 19320487DOI: 10.1021/jm801475n 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3.1 Å) |
構造検証レポート
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