3F9P

Crystal structure of myeloperoxidase from human leukocytes

Summary for 3F9P

Entry DOI	10.2210/pdb3f9p/pdb
Descriptor	Myeloperoxidase, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (8 entities in total)
Functional Keywords	imidazolate, myeloperoxidase, heme to protein linkage, peroxidase-cyclooxygenase superfamily, disease mutation, glycoprotein, hydrogen peroxide, iron, lysosome, metal-binding, oxidation, oxidoreductase, disulfide bond, heme, peroxidase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	136932.35
Authors	Carpena, X.,Fita, I.,Obinger, C. (deposition date: 2008-11-14, release date: 2009-07-14, Last modification date: 2023-12-27)
Primary citation	Carpena, X.,Vidossich, P.,Schroettner, K.,Calisto, B.M.,Banerjee, S.,Stampler, J.,Soudi, M.,Furtmuller, P.G.,Rovira, C.,Fita, I.,Obinger, C. Essential role of proximal histidine-asparagine interaction in Mammalian peroxidases. J.Biol.Chem., 284:25929-25937, 2009 Cited by PubMed: 19608745 DOI: 10.1074/jbc.M109.002154 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.93 Å)

Structure validation