3F9P

Crystal structure of myeloperoxidase from human leukocytes

3F9P の概要

• エントリーDOI: 10.2210/pdb3f9p/pdb
• 分子名称: Myeloperoxidase, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (8 entities in total)
• 機能のキーワード: imidazolate, myeloperoxidase, heme to protein linkage, peroxidase-cyclooxygenase superfamily, disease mutation, glycoprotein, hydrogen peroxide, iron, lysosome, metal-binding, oxidation, oxidoreductase, disulfide bond, heme, peroxidase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 136932.35

構造登録者

Carpena, X.,Fita, I.,Obinger, C. (登録日: 2008-11-14, 公開日: 2009-07-14, 最終更新日: 2023-12-27)

• 主引用文献: Carpena, X.,Vidossich, P.,Schroettner, K.,Calisto, B.M.,Banerjee, S.,Stampler, J.,Soudi, M.,Furtmuller, P.G.,Rovira, C.,Fita, I.,Obinger, C.; Essential role of proximal histidine-asparagine interaction in Mammalian peroxidases.; J.Biol.Chem., 284:25929-25937, 2009; PubMed: 19608745; DOI: 10.1074/jbc.M109.002154

実験手法

X-RAY DIFFRACTION (2.93 Å)