3EUV

Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10, W102T, Y154T) in complex with BiotinGPP

Summary for 3EUV

• Entry DOI: 10.2210/pdb3euv/pdb
• Related: 3EU5
• Descriptor: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, Protein farnesyltransferase subunit beta, ZINC ION, ... (5 entities in total)
• Functional Keywords: protein prenylation, prenylome analysis, prenyltransferase, transferase, metal-binding, phosphoprotein, zinc
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 2
• Total formula weight: 92321.24

Authors

Guo, Z.,Nguyen, U.T.T.,Delon, C.,Bon, R.S.,Blankenfeldt, W.,Goody, R.S.,Waldmann, H.,Wolters, D.,Alexandrov, K. (deposition date: 2008-10-11, release date: 2009-07-07, Last modification date: 2023-11-01)

• Primary citation: Nguyen, U.T.T.,Guo, Z.,Delon, C.,Wu, Y.,Deraeve, C.,Franzel, B.,Bon, R.S.,Blankenfeldt, W.,Goody, R.S.,Waldmann, H.,Wolters, D.,Alexandrov, K.; Analysis of the eukaryotic prenylome by isoprenoid affinity tagging; Nat.Chem.Biol., 5:227-235, 2009; PubMed: 19219049; DOI: 10.1038/nchembio.149

Experimental method

X-RAY DIFFRACTION (2.75 Å)