3ERK

THE COMPLEX STRUCTURE OF THE MAP KINASE ERK2/SB220025

Summary for 3ERK

Entry DOI	10.2210/pdb3erk/pdb
Descriptor	EXTRACELLULAR REGULATED KINASE 2, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE (3 entities in total)
Functional Keywords	transferase, serine/threonine-protein kinase, map kinase, erk2
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	1
Total formula weight	42497.82
Authors	Wang, Z.,Canagarajah, B.,Boehm, J.C.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J. (deposition date: 1998-07-09, release date: 1999-07-22, Last modification date: 2023-08-09)
Primary citation	Wang, Z.,Canagarajah, B.J.,Boehm, J.C.,Kassisa, S.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J. Structural basis of inhibitor selectivity in MAP kinases. Structure, 6:1117-1128, 1998 Cited by PubMed: 9753691 DOI: 10.1016/S0969-2126(98)00113-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation