3ERI

First structural evidence of substrate specificity in mammalian peroxidases: Crystal structures of substrate complexes with lactoperoxidases from two different species

3ERI の概要

• エントリーDOI: 10.2210/pdb3eri/pdb
• 関連するPDBエントリー: 2R5L 3BXI 3ERH
• 分子名称: Lactoperoxidase, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: lactopeoxidase, complex, heme, oxidoreductase, antibiotic, antimicrobial, cleavage on pair of basic residues, glycoprotein, hydrogen peroxide, iron, metal-binding, peroxidase, secreted
• 由来する生物種: Bos taurus (Bovine)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 71536.22

構造登録者

Singh, A.K.,Singh, N.,Sheikh, I.A.,Sinha, M.,Bhushan, A.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P. (登録日: 2008-10-02, 公開日: 2009-03-31, 最終更新日: 2023-11-01)

• 主引用文献: Sheikh, I.A.,Singh, A.K.,Singh, N.,Sinha, M.,Singh, S.B.,Bhushan, A.,Kaur, P.,Srinivasan, A.,Sharma, S.,Singh, T.P.; Structural Evidence of Substrate Specificity in Mammalian Peroxidases: STRUCTURE OF THE THIOCYANATE COMPLEX WITH LACTOPEROXIDASE AND ITS INTERACTIONS AT 2.4 A RESOLUTION; J.Biol.Chem., 284:14849-14856, 2009; PubMed: 19339248; DOI: 10.1074/jbc.M807644200

実験手法

X-RAY DIFFRACTION (2.5 Å)