3EKA

Crystal structure of the complex of hyaluranidase trimer with ascorbic acid at 3.1 A resolution reveals the locations of three binding sites

Replaces:  2PK1

Summary for 3EKA

• Entry DOI: 10.2210/pdb3eka/pdb
• Related: 2YVV 2YW0
• Descriptor: Hyaluronidase, phage associated, ASCORBIC ACID (3 entities in total)
• Functional Keywords: ascorbic acid complex, lyase, hyaluronan lyase, phage tail fibre, triple-stranded
• Biological source: Streptococcus pyogenes
• Total number of polymer chains: 1
• Total formula weight: 36325.54

Authors

Mishra, P.,Ethayathulla, A.S.,Prem Kumar, R.,Singh, N.,Sharma, S.,Kaur, P.,Bhakuni, V.,Singh, T.P. (deposition date: 2008-09-19, release date: 2009-09-29, Last modification date: 2023-11-01)

• Primary citation: Mishra, P.,Prem Kumar, R.,Ethayathulla, A.S.,Singh, N.,Sharma, S.,Perbandt, M.,Betzel, C.,Kaur, P.,Srinivasan, A.,Bhakuni, V.,Singh, T.P.; Polysaccharide binding sites in hyaluronate lyase--crystal structures of native phage-encoded hyaluronate lyase and its complexes with ascorbic acid and lactose.; Febs J., 276:3392-3402, 2009; PubMed: 19438710; DOI: 10.1111/j.1742-4658.2009.07065.x

Experimental method

X-RAY DIFFRACTION (3.1 Å)