3EG6
Structure of WDR5 bound to MLL1 peptide
Summary for 3EG6
Entry DOI | 10.2210/pdb3eg6/pdb |
Descriptor | WD repeat-containing protein 5, MLL-1 peptide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | wdr5, mll1, win motif, mll core complex, histone h3, lysine methylation, nucleus, phosphoprotein, wd repeat, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P61964 Nucleus . MLL cleavage product N320: Nucleus. MLL cleavage product C180: Nucleus: Q03164 |
Total number of polymer chains | 2 |
Total formula weight | 35932.64 |
Authors | Patel, A.,Dharmarajan, V.,Cosgrove, M.S. (deposition date: 2008-09-10, release date: 2008-09-30, Last modification date: 2023-08-30) |
Primary citation | Patel, A.,Dharmarajan, V.,Cosgrove, M.S. Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide. J.Biol.Chem., 283:32158-32161, 2008 Cited by PubMed: 18829459DOI: 10.1074/jbc.C800164200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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