3EFT

Crystal structure of the complex between Carbonic Anhydrase II and a spin-labeled sulfonamide incorporating TEMPO moiety

3EFT の概要

• エントリーDOI: 10.2210/pdb3eft/pdb
• 分子名称: Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
• 機能のキーワード: carbonic anhydrase, inhibitors, radicals, oxo-acid, lyase
• 細胞内の位置: Cytoplasm : P00918
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29976.04

構造登録者

Temperini, C.,Cecchi, A.,Scozzafava, A.,Supuran, C.T. (登録日: 2008-09-10, 公開日: 2009-09-08, 最終更新日: 2023-11-01)

• 主引用文献: Ciani, L.,Cecchi, A.,Temperini, C.,Supuran, C.T.,Ristori, S.; Dissecting the Inhibition Mechanism of Cytosolic versus Transmembrane Carbonic Anhydrases by ESR; J.Phys.Chem.B, 113:13998-14005, 2009; PubMed: 19778001; DOI: 10.1021/jp906593c

実験手法

X-RAY DIFFRACTION (1.85 Å)