3EFI

Carbonic anhydrase activators: Kinetic and X-ray crystallographic study for the interaction of d- and l-tryptophan with the mammalian isoforms I-XIV

3EFI の概要

• エントリーDOI: 10.2210/pdb3efi/pdb
• 分子名称: Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ... (5 entities in total)
• 機能のキーワード: carbonic anhydrase, activators, aminoacids, oxo-acid, acetylation, cytoplasm, disease mutation, lyase, metal-binding, polymorphism, zinc
• 細胞内の位置: Cytoplasm : P00918
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29880.40

構造登録者

Temperini, C.,Innocenti, A.,Scozzafava, A.,Supuran, C.T. (登録日: 2008-09-09, 公開日: 2008-09-30, 最終更新日: 2023-11-01)

• 主引用文献: Temperini, C.,Innocenti, A.,Scozzafava, A.,Supuran, C.T.; Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV; Bioorg.Med.Chem., 16:8373-8378, 2008; PubMed: 18774300; DOI: 10.1016/j.bmc.2008.08.043

実験手法

X-RAY DIFFRACTION (1.75 Å)