3ECW
Crystal structure of the ALS-related pathological mutant T54R of human apo Cu,Zn Superoxide Dismutase (SOD1)
Summary for 3ECW
Entry DOI | 10.2210/pdb3ecw/pdb |
Related | 3ECU 3ECV |
Descriptor | Superoxide dismutase [Cu-Zn] (2 entities in total) |
Functional Keywords | human superoxide dismutase, homodimeric protein, apo protein, aggregation, als, mutant, acetylation, amyotrophic lateral sclerosis, antioxidant, copper, cytoplasm, disease mutation, metal-binding, oxidoreductase, ubl conjugation, zinc |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P00441 |
Total number of polymer chains | 4 |
Total formula weight | 63534.60 |
Authors | Calderone, V. (deposition date: 2008-09-02, release date: 2009-05-19, Last modification date: 2023-08-30) |
Primary citation | Banci, L.,Bertini, I.,Boca, M.,Calderone, V.,Cantini, F.,Girotto, S.,Vieru, M. Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants. Proc.Natl.Acad.Sci.USA, 106:6980-6985, 2009 Cited by PubMed: 19369197DOI: 10.1073/pnas.0809845106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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