3DX6

Crystal Structure of B*4402 presenting a 10mer EBV epitope

3DX6 の概要

• エントリーDOI: 10.2210/pdb3dx6/pdb
• 関連するPDBエントリー: 3DX7 3DX8 3DX9 3DXA
• 分子名称: HLA class I histocompatibility complex HLA-B*4402, Beta-2-microglobulin, EBV decapeptide epitope, ... (6 entities in total)
• 機能のキーワード: mhc, glycoprotein, glycation, host-virus interaction, immune response, membrane, mhc i, transmembrane, pyrrolidone carboxylic acid, disease mutation, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P30481; Secreted: P61769; Host nucleus matrix: P03204
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45726.42

構造登録者

Archbold, J.K.,Ely, L.K.,Rossjohn, J. (登録日: 2008-07-23, 公開日: 2009-01-27, 最終更新日: 2011-07-13)

• 主引用文献: Archbold, J.K.,Macdonald, W.A.,Gras, S.,Ely, L.K.,Miles, J.J.,Bell, M.J.,Brennan, R.M.,Beddoe, T.,Wilce, M.C.,Clements, C.S.,Purcell, A.W.,McCluskey, J.,Burrows, S.R.,Rossjohn, J.; Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.; J.Exp.Med., 206:209-219, 2009; PubMed: 19139173; DOI: 10.1084/jem.20082136

実験手法

X-RAY DIFFRACTION (1.701 Å)