3DOZ
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3k
Summary for 3DOZ
Entry DOI | 10.2210/pdb3doz/pdb |
Related | 2GLL 3DOY 3DP0 3DP1 3DP2 3DP3 |
Descriptor | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ... (5 entities in total) |
Functional Keywords | fabz complex, lyase |
Biological source | Helicobacter pylori (Campylobacter pylori) |
Cellular location | Cytoplasm (By similarity): Q5G940 |
Total number of polymer chains | 6 |
Total formula weight | 111156.23 |
Authors | |
Primary citation | He, L.,Zhang, L.,Liu, X.,Li, X.,Zheng, M.,Li, H.,Yu, K.,Chen, K.,Shen, X.,Jiang, H.,Liu, H. Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. J.Med.Chem., 52:2465-2481, 2009 Cited by PubMed: 19309082DOI: 10.1021/jm8015602 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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