3DND

cAMP-dependent protein kinase PKA catalytic subunit with PKI-5-24

3DND の概要

• エントリーDOI: 10.2210/pdb3dnd/pdb
• 関連するPDBエントリー: 3DNE
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 5-benzyl-1,3-thiazol-2-amine, ... (4 entities in total)
• 機能のキーワード: atp-binding, kinase, lipoprotein, myristate, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase, camp, protein kinase inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Bos taurus (bovine,cow,domestic cattle,domestic cow); 詳細
• 細胞内の位置: Cytoplasm: P00517
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43124.08

構造登録者

Schiffer, A.,Wendt, K.U. (登録日: 2008-07-02, 公開日: 2009-06-23, 最終更新日: 2013-10-09)

• 主引用文献: Orts, J.,Tuma, J.,Reese, M.,Grimm, S.K.,Monecke, P.,Bartoschek, S.,Schiffer, A.,Wendt, K.U.,Griesinger, C.,Carlomagno, T.; Crystallography-independent determination of ligand binding modes; Angew.Chem.Int.Ed.Engl., 47:7736-7740, 2008; PubMed: 18767090; DOI: 10.1002/anie.200801792

実験手法

X-RAY DIFFRACTION (2.26 Å)