3DMT

Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in complex with the irreversible iodoacetate inhibitor

Summary for 3DMT

• Entry DOI: 10.2210/pdb3dmt/pdb
• Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, glycosomal, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ... (5 entities in total)
• Functional Keywords: active-site carboxymethylation, irreversible inhibitor complex, trypanosoma cruzi, glycolysis, glycosome, nad, oxidoreductase
• Biological source: Trypanosoma cruzi; More
• Total number of polymer chains: 4
• Total formula weight: 159253.99

Authors

Guido, R.V.C.,Balliano, T.L.,Andricopulo, A.D.,Oliva, G. (deposition date: 2008-07-01, release date: 2008-10-21, Last modification date: 2023-08-30)

• Primary citation: Guido, R.V.C.,Balliano, T.L.,Andricopulo, A.D.,Oliva, G.; Kinetic and Crystallographic Studies on Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in Complex with Iodoacetate.; Letters in drug design & discovery, 6:210-214, 2009

Experimental method

X-RAY DIFFRACTION (2.3 Å)