3DMT

Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in complex with the irreversible iodoacetate inhibitor

3DMT の概要

• エントリーDOI: 10.2210/pdb3dmt/pdb
• 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, glycosomal, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: active-site carboxymethylation, irreversible inhibitor complex, trypanosoma cruzi, glycolysis, glycosome, nad, oxidoreductase
• 由来する生物種: Trypanosoma cruzi; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 159253.99

構造登録者

Guido, R.V.C.,Balliano, T.L.,Andricopulo, A.D.,Oliva, G. (登録日: 2008-07-01, 公開日: 2008-10-21, 最終更新日: 2023-08-30)

• 主引用文献: Guido, R.V.C.,Balliano, T.L.,Andricopulo, A.D.,Oliva, G.; Kinetic and Crystallographic Studies on Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in Complex with Iodoacetate.; Letters in drug design & discovery, 6:210-214, 2009

実験手法

X-RAY DIFFRACTION (2.3 Å)