3DJF

Crystal Structure of Schistosoma mansoni Purine Nucleoside Phosphorylase in a complex with BCX-34

3DJF の概要

• エントリーDOI: 10.2210/pdb3djf/pdb
• 関連するPDBエントリー: 1tcu 1tcv 1td1
• 分子名称: Purine-nucleoside phosphorylase, SULFATE ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
• 機能のキーワード: purine nucleoside phosphorylase, bcx34, inhibitor, glycosyltransferase, transferase
• 由来する生物種: Schistosoma mansoni (Blood fluke)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 94742.03

構造登録者

Postigo, M.P.,Pereira, H.M.,Oliva, G.,Andricopulo, A.D. (登録日: 2008-06-23, 公開日: 2009-06-30, 最終更新日: 2024-02-21)

• 主引用文献: Castilho, M.S.,Postigo, M.P.,Pereira, H.M.,Oliva, G.,Andricopulo, A.D.; Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies.; Bioorg.Med.Chem., 18:1421-1427, 2010; PubMed: 20129792; DOI: 10.1016/j.bmc.2010.01.022

実験手法

X-RAY DIFFRACTION (2.302 Å)