3DHC

1.3 Angstrom Structure of N-Acyl Homoserine Lactone Hydrolase with the Product N-Hexanoyl-L-Homocysteine Bound to The catalytic Metal Center

3DHC の概要

• エントリーDOI: 10.2210/pdb3dhc/pdb
• 関連するPDBエントリー: 2A7M 2R2D 3DHA 3DHB
• 分子名称: N-Acyl Homoserine Lactone Hydrolase, ZINC ION, N-hexanoyl-L-homocysteine, ... (5 entities in total)
• 機能のキーワード: zinc bimetallohydrolase, qourum quenching, n-acyl homocysteine thiolactone, product complex, ahl lactonase, general acid, catalytic mechanism, hydrolase
• 由来する生物種: Bacillus thuringiensis serovar kurstaki
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29581.35

構造登録者

Liu, D.,Momb, J.,Thomas, P.W.,Moulin, A.,Petsko, G.A.,Fast, W.,Ringe, D. (登録日: 2008-06-17, 公開日: 2008-07-29, 最終更新日: 2023-08-30)

• 主引用文献: Liu, D.,Momb, J.,Thomas, P.W.,Moulin, A.,Petsko, G.A.,Fast, W.,Ringe, D.; Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures.; Biochemistry, 47:7706-7714, 2008; PubMed: 18627129; DOI: 10.1021/bi800368y

実験手法

X-RAY DIFFRACTION (1.3 Å)