3DHA

An Ultral High Resolution Structure of N-Acyl Homoserine Lactone Hydrolase with the Product N-Hexanoyl-L-Homoserine Bound at An Alternative Site

3DHA の概要

• エントリーDOI: 10.2210/pdb3dha/pdb
• 関連するPDBエントリー: 2A7M 2R2D 3DHB 3DHC
• 分子名称: N-Acyl Homoserine Lactone Hydrolase, ZINC ION, N-hexanoyl-L-homoserine, ... (5 entities in total)
• 機能のキーワード: zinc bimetallohydrolase, quorum quenching, n-acyl homoserine lactone, alternative binding site, product complex, ahl lactonase, hydrolase
• 由来する生物種: Bacillus thuringiensis serovar kurstaki
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29381.10

構造登録者

Liu, D.,Momb, J.,Thomas, P.W.,Moulin, A.,Petsko, G.A.,Fast, W.,Ringe, D. (登録日: 2008-06-17, 公開日: 2008-07-29, 最終更新日: 2023-08-30)

• 主引用文献: Liu, D.,Momb, J.,Thomas, P.W.,Moulin, A.,Petsko, G.A.,Fast, W.,Ringe, D.; Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures.; Biochemistry, 47:7706-7714, 2008; PubMed: 18627129; DOI: 10.1021/bi800368y

実験手法

X-RAY DIFFRACTION (0.95 Å)