3DFC

Crystal structure of a glycine-rich loop mutant of the death associated protein kinase catalytic domain with AMPPNP

3DFC の概要

• エントリーDOI: 10.2210/pdb3dfc/pdb
• 関連するPDBエントリー: 1JKL
• 分子名称: Death-associated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total)
• 機能のキーワード: kinase domain, glycine-rich loop mutation, amppnp, ank repeat, apoptosis, atp-binding, calmodulin-binding, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Isoform 1: Cytoplasm. Isoform 2: Cytoplasm: P53355
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34432.81

構造登録者

McNamara, L.K.,Schavocky, J.P.,Watterson, D.M.,Brunzelle, J.S. (登録日: 2008-06-11, 公開日: 2009-05-26, 最終更新日: 2023-08-30)

• 主引用文献: McNamara, L.K.,Schavocky, J.P.,Watterson, D.M.,Brunzelle, J.S.; High resolution crystal structures of the death associated protein kinase catalytic domain with a key point mutation in the glycine-rich loop; To be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)