3DBQ

Crystal structure of TTK kinase domain

3DBQ の概要

• エントリーDOI: 10.2210/pdb3dbq/pdb
• 分子名称: Dual specificity protein kinase TTK (2 entities in total)
• 機能のキーワード: mps1 structure, kinase activation, phosphorylation, atp-binding, kinase, nucleotide-binding, phosphoprotein, polymorphism, serine/threonine-protein kinase, transferase, tyrosine-protein kinase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39278.00

構造登録者

Wang, W.,Yang, Y.T.,Gao, Y.F.,Zhu, S.C.,Wang, F.,Old, W.,Xu, Q.B.,Resing, K.,Ahn, N.,Lei, M.,Liu, X.D. (登録日: 2008-06-02, 公開日: 2009-02-10, 最終更新日: 2011-07-13)

• 主引用文献: Wang, W.,Yang, Y.T.,Gao, Y.F.,Xu, Q.B.,Wang, F.,Zhu, S.C.,Old, W.,Resing, K.,Ahn, N.,Lei, M.,Liu, X.D.; Structural and Mechanistic Insights into Mps1 Kinase Activation; J.CELL.MOL.MED., 13:1679-1694, 2008; PubMed: 19120698; DOI: 10.1111/j.1582-4934.2008.00605.x

実験手法

X-RAY DIFFRACTION (2.7 Å)