3D7J

SCO6650, a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor

3D7J の概要

• エントリーDOI: 10.2210/pdb3d7j/pdb
• 分子名称: Uncharacterized protein SCO6650, SODIUM ION, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: t-fold, unknown function
• 由来する生物種: Streptomyces coelicolor
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 100258.47

構造登録者

Spoonamore, J.E.,Roberts, S.A.,Heroux, A.,Bandarian, V. (登録日: 2008-05-21, 公開日: 2008-10-21, 最終更新日: 2024-10-30)

主引用文献

Spoonamore, J.E.,Roberts, S.A.,Heroux, A.,Bandarian, V.
Structure of a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor.
Acta Crystallogr.,Sect.F, 64:875-879, 2008

PubMed Abstract: The X-ray crystal structure of the 6-pyruvoyltetrahydropterin synthase (PTPS) homolog from Streptomyces coelicolor, SCO 6650, was solved at 1.5 A resolution. SCO 6650 forms a hexameric T-fold that closely resembles other PTPS proteins. The biological activity of SCO 6650 is unknown, but it lacks both a required active-site zinc metal ion and the essential catalytic triad and does not catalyze the PTPS reaction. However, SCO 6650 maintains active-site residues consistent with binding a pterin-like substrate.

PubMed: 18931427
DOI: 10.1107/S1744309108027048

実験手法

X-RAY DIFFRACTION (1.45 Å)