3D2X

Structure of the thiamine pyrophosphate-specific riboswitch bound to oxythiamine pyrophosphate

Summary for 3D2X

Entry DOI	10.2210/pdb3d2x/pdb
Related	2cky 3d2g 3d2v
Descriptor	TPP-specific riboswitch, MAGNESIUM ION, 3-[(4-hydroxy-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, ... (4 entities in total)
Functional Keywords	rna, riboswitch, thiamine pyrophosphate, oxythiamine pyrophosphate, antibiotic, drugs, complex
Biological source	Arabidopsis thaliana
Total number of polymer chains	2
Total formula weight	51086.24
Authors	Thore, S.,Frick, C.,Ban, N. (deposition date: 2008-05-09, release date: 2008-07-01, Last modification date: 2023-08-30)
Primary citation	Thore, S.,Frick, C.,Ban, N. Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch J.Am.Chem.Soc., 130:8116-8117, 2008 Cited by PubMed: 18533652 DOI: 10.1021/ja801708e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation