3D2X

Structure of the thiamine pyrophosphate-specific riboswitch bound to oxythiamine pyrophosphate

3D2X の概要

• エントリーDOI: 10.2210/pdb3d2x/pdb
• 関連するPDBエントリー: 2cky 3d2g 3d2v
• 分子名称: TPP-specific riboswitch, MAGNESIUM ION, 3-[(4-hydroxy-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, ... (4 entities in total)
• 機能のキーワード: rna, riboswitch, thiamine pyrophosphate, oxythiamine pyrophosphate, antibiotic, drugs, complex
• 由来する生物種: Arabidopsis thaliana
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51086.24

構造登録者

Thore, S.,Frick, C.,Ban, N. (登録日: 2008-05-09, 公開日: 2008-07-01, 最終更新日: 2023-08-30)

• 主引用文献: Thore, S.,Frick, C.,Ban, N.; Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch; J.Am.Chem.Soc., 130:8116-8117, 2008; PubMed: 18533652; DOI: 10.1021/ja801708e

実験手法

X-RAY DIFFRACTION (2.5 Å)