3CXD

Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide

Summary for 3CXD

• Entry DOI: 10.2210/pdb3cxd/pdb
• Descriptor: Fab fragment of anti-osteopontin antibody 23C3, Light chain, Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, a peptide from osteopontin, ... (4 entities in total)
• Functional Keywords: fab, osteopontin, opn, antibody-antigen complex, immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Secreted: P10451
• Total number of polymer chains: 3
• Total formula weight: 48307.53

Authors

Du, J.,Yang, H.,Zhong, C.,Ding, J. (deposition date: 2008-04-24, release date: 2008-10-14, Last modification date: 2023-11-01)

• Primary citation: Du, J.,Hou, S.,Zhong, C.,Lai, Z.,Yang, H.,Dai, J.,Zhang, D.,Wang, H.,Guo, Y.,Ding, J.; Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis; J.Mol.Biol., 382:835-842, 2008; PubMed: 18694758; DOI: 10.1016/j.jmb.2008.07.075

Experimental method

X-RAY DIFFRACTION (2.8 Å)