3CXD

Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide

3CXD の概要

• エントリーDOI: 10.2210/pdb3cxd/pdb
• 分子名称: Fab fragment of anti-osteopontin antibody 23C3, Light chain, Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, a peptide from osteopontin, ... (4 entities in total)
• 機能のキーワード: fab, osteopontin, opn, antibody-antigen complex, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Secreted: P10451
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 48307.53

構造登録者

Du, J.,Yang, H.,Zhong, C.,Ding, J. (登録日: 2008-04-24, 公開日: 2008-10-14, 最終更新日: 2023-11-01)

• 主引用文献: Du, J.,Hou, S.,Zhong, C.,Lai, Z.,Yang, H.,Dai, J.,Zhang, D.,Wang, H.,Guo, Y.,Ding, J.; Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis; J.Mol.Biol., 382:835-842, 2008; PubMed: 18694758; DOI: 10.1016/j.jmb.2008.07.075

実験手法

X-RAY DIFFRACTION (2.8 Å)