3CRO

THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION

3CRO の概要

• エントリーDOI: 10.2210/pdb3cro/pdb
• 分子名称: DNA (5'-D(*AP*AP*GP*TP*AP*CP*AP*AP*AP*CP*TP*TP*TP*CP*TP*TP*G P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*GP*AP*AP*AP*GP*TP*TP*TP*GP*T P*AP*CP*T)-3'), PROTEIN (434 CRO), ... (4 entities in total)
• 機能のキーワード: protein-dna complex, double helix, transcription-dna complex, transcription/dna
• 由来する生物種: Phage 434
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 28416.25

構造登録者

Mondragon, A.,Harrison, S.C. (登録日: 1990-07-06, 公開日: 1991-10-15, 最終更新日: 2024-02-21)

主引用文献

Mondragon, A.,Harrison, S.C.
The phage 434 Cro/OR1 complex at 2.5 A resolution.
J.Mol.Biol., 219:321-334, 1991

PubMed Abstract: The crystal structure of phage 434 Cro protein in complex with a 20 base-pair DNA fragment has been determined to 2.5 A resolution. The DNA fragment contains the sequence of the OR1 operator site. The structure shows a bent conformation for the DNA, straighter at the center and more bent at the ends. The central base-pairs adopt conformations with significant deviations from coplanarity. The two molecules interact extensively along their common interface, both through hydrogen bonds and van der Waals interactions. The significance of these interactions for operator binding and recognition is discussed.

PubMed: 2038059
DOI: 10.1016/0022-2836(91)90568-Q

実験手法

X-RAY DIFFRACTION (2.5 Å)