3CJB
Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with Gelsolin-segment 1
Summary for 3CJB
Entry DOI | 10.2210/pdb3cjb/pdb |
Related | 3CJC |
Descriptor | Actin, alpha skeletal muscle, Gelsolin, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | cross-linked dimer, atp-binding, cytoskeleton, methylation, muscle protein, nucleotide-binding, phosphoprotein, structural protein, actin capping, actin-binding, alternative initiation, amyloid, disease mutation, secreted |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton: P68135 Isoform 2: Cytoplasm, cytoskeleton. Isoform 1: Secreted: P06396 |
Total number of polymer chains | 2 |
Total formula weight | 56756.12 |
Authors | Sawaya, M.R.,Kudryashov, D.S.,Pashkov, I.,Reisler, E.,Yeates, T.O. (deposition date: 2008-03-12, release date: 2008-03-25, Last modification date: 2024-02-21) |
Primary citation | Kudryashov, D.S.,Durer, Z.A.,Ytterberg, A.J.,Sawaya, M.R.,Pashkov, I.,Prochazkova, K.,Yeates, T.O.,Loo, R.R.,Loo, J.A.,Satchell, K.J.,Reisler, E. Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc.Natl.Acad.Sci.USA, 105:18537-18542, 2008 Cited by PubMed: 19015515DOI: 10.1073/pnas.0808082105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.21 Å) |
Structure validation
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