3CFW

L-selectin lectin and EGF domains

3CFW の概要

• エントリーDOI: 10.2210/pdb3cfw/pdb
• 関連するPDBエントリー: 1ESL 1G1Q 1G1R 1G1S 1G1T
• 分子名称: L-selectin, alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: l-selectin, lectin, egf, cell adhesion, egf-like domain, glycoprotein, membrane, sushi, transmembrane
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P14151
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20381.64

構造登録者

Mehta, P.,Oganesyan, V.,Terzyan, S.,Mather, T.,McEver, R.P. (登録日: 2008-03-04, 公開日: 2008-03-18, 最終更新日: 2023-08-30)

• 主引用文献: Mehta-D'souza, P.,Klopocki, A.G.,Oganesyan, V.,Terzyan, S.,Mather, T.,Li, Z.,Panicker, S.R.,Zhu, C.,McEver, R.P.; Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.; J.Biol.Chem., 292:2510-2518, 2017; PubMed: 28011641; DOI: 10.1074/jbc.M116.767186

実験手法

X-RAY DIFFRACTION (2.2 Å)