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3CF9

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with apigenin

Summary for 3CF9
Entry DOI10.2210/pdb3cf9/pdb
Related2GLL 3CF8 3D04
Descriptor(3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, ... (5 entities in total)
Functional Keywordsfabz complex, apigenin, cytoplasm, lipid a biosynthesis, lipid synthesis, lyase
Biological sourceHelicobacter pylori
Cellular locationCytoplasm (By similarity): Q5G940
Total number of polymer chains6
Total formula weight110470.51
Authors
Zhang, L.,Wu, D.,Liu, W.,Shen, X.,Jiang, H. (deposition date: 2008-03-03, release date: 2008-12-09, Last modification date: 2024-03-13)
Primary citationZhang, L.,Kong, Y.,Wu, D.,Zhang, H.,Wu, J.,Chen, J.,Ding, J.,Hu, L.,Jiang, H.,Shen, X.
Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay
Protein Sci., 17:1971-1978, 2008
Cited by
PubMed: 18780820
DOI: 10.1110/ps.036186.108
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

217705

数据于2024-03-27公开中

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