3CF9

Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with apigenin

3CF9 の概要

• エントリーDOI: 10.2210/pdb3cf9/pdb
• 関連するPDBエントリー: 2GLL 3CF8 3D04
• 分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, ... (5 entities in total)
• 機能のキーワード: fabz complex, apigenin, cytoplasm, lipid a biosynthesis, lipid synthesis, lyase
• 由来する生物種: Helicobacter pylori
• 細胞内の位置: Cytoplasm (By similarity): Q5G940
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 110470.51

構造登録者

Zhang, L.,Wu, D.,Liu, W.,Shen, X.,Jiang, H. (登録日: 2008-03-03, 公開日: 2008-12-09, 最終更新日: 2024-03-13)

• 主引用文献: Zhang, L.,Kong, Y.,Wu, D.,Zhang, H.,Wu, J.,Chen, J.,Ding, J.,Hu, L.,Jiang, H.,Shen, X.; Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay; Protein Sci., 17:1971-1978, 2008; PubMed: 18780820; DOI: 10.1110/ps.036186.108

実験手法

X-RAY DIFFRACTION (2.6 Å)