3CF8
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with quercetin
Summary for 3CF8
Entry DOI | 10.2210/pdb3cf8/pdb |
Related | 2GLL 3CF9 3D04 |
Descriptor | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, CHLORIDE ION, BENZAMIDINE, ... (5 entities in total) |
Functional Keywords | fabz complex, quercetin, cytoplasm, lipid a biosynthesis, lipid synthesis, lyase |
Biological source | Helicobacter pylori |
Cellular location | Cytoplasm : Q5G940 |
Total number of polymer chains | 6 |
Total formula weight | 110774.82 |
Authors | |
Primary citation | Zhang, L.,Kong, Y.,Wu, D.,Zhang, H.,Wu, J.,Chen, J.,Ding, J.,Hu, L.,Jiang, H.,Shen, X. Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay Protein Sci., 17:1971-1978, 2008 Cited by PubMed: 18780820DOI: 10.1110/ps.036186.108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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