3CC5

H-2Db complex with human gp100

3CC5 の概要

• エントリーDOI: 10.2210/pdb3cc5/pdb
• 分子名称: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, nonameric peptide from Melanocyte protein Pmel 17, ... (6 entities in total)
• 機能のキーワード: murine mhc, glycoprotein, immune response, membrane, mhc i, transmembrane, immunoglobulin domain, secreted, melanin biosynthesis, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887; Endoplasmic reticulum membrane; Single-pass type I membrane protein. M-alpha: Secreted: P40967
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 90739.52

構造登録者

Badia-Martinez, D.,Achour, A. (登録日: 2008-02-24, 公開日: 2009-03-03, 最終更新日: 2023-11-01)

• 主引用文献: van Stipdonk, M.J.,Badia-Martinez, D.,Sluijter, M.,Offringa, R.,van Hall, T.,Achour, A.; Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.; Cancer Res., 69:7784-7792, 2009; PubMed: 19789338; DOI: 10.1158/0008-5472.CAN-09-1724

実験手法

X-RAY DIFFRACTION (1.91 Å)