3CA7
High Resolution Crystal Structure of the EGF domain of Spitz
Summary for 3CA7
Entry DOI | 10.2210/pdb3ca7/pdb |
Descriptor | Protein spitz (2 entities in total) |
Functional Keywords | spitz, argos, egf, developmental protein, differentiation, egf-like domain, endoplasmic reticulum, glycoprotein, golgi apparatus, membrane, neurogenesis, transmembrane, hormone-signaling protein complex, hormone/signaling protein |
Biological source | Drosophila melanogaster (Fruit fly) |
Cellular location | Cell membrane; Single-pass type I membrane protein: Q01083 |
Total number of polymer chains | 1 |
Total formula weight | 6012.86 |
Authors | Klein, D.E.,Stayrook, S.E.,Lemmon, M.A. (deposition date: 2008-02-19, release date: 2008-05-20, Last modification date: 2023-08-30) |
Primary citation | Klein, D.E.,Stayrook, S.E.,Shi, F.,Narayan, K.,Lemmon, M.A. Structural basis for EGFR ligand sequestration by Argos. Nature, 453:1271-1275, 2008 Cited by PubMed: 18500331DOI: 10.1038/nature06978 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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